The Hematology Faculty


Divison Chief

		Linda M. Boxer, MD, PhD, Professor The molecular mechanisms of deregulation of the oncogenes, c-myc and bcl-2, by translocation into immunoglobulin loci How deregulation of these oncogenes disrupts the normal regulatory control mechanisms in hematopoietic cells Identification of critical genes and pathways in acute lymphoblastic leukemia in response to chemotherapeutic agents


Full and Emeritus Professors

		Lawrence L.K. Leung, MD, Professor The Maureen Lyles D'Ambrogio Professor The discovery and development of new antithrombotic reagents, targeting plasma proteases and their inhibitors, and cell adhesive proteins and their receptors on platelets and endothelial cells Approaches include basic molecular and protein biochemistry to the evaluation in appropriate animal models



		Peter L. Greenberg, MD, Professor, Emeritus (Active) The role and mechanisms of programmed cell death (apoptosis), oncoprotein/oncogene expression, and anti-angiogenesis in hemopoietic regulation Focus is given to evaluating these processes in the evolution of myelodysplastic syndromes and acute myeloid leukemia in vitro and in vivo, with emphasis on the impact of hemopoietic growth factors Development of clinical protocols for treating myelodysplastic syndrome and acute myeloid leukemias Director, MDS Center



		Stanley L. Schrier, MD, Professor, Emeritus (Active) Red cell biology with emphasis on the pathophysiology and cell biology of the thalassemias, the causes of anemia in malaria, and the complex consequences of anemia in the aged President, American Society of Hematology (ASH)

Lawrence Tim Goodnough, MD, Professor, Pathology & Medicine

Beverly S. Mitchell, MD, Professor of Medicine
George E. Becker Professor of Medicine

Role of nucleotides in regulating nucleolar organization, function and cell proliferation
Novel therapies for acute leukemia with correlative studies
Function of a novel DNA repair protein with ubiquitin ligase activity



		James L. Zehnder, MD, Professor, Pathology & Medicine Clinical and laboratory investigation of thrombosis and bleeding disorders Molecular diagnostic testing for inherited thrombophilia and hematololymphoid malignancy


Associate Professors

		Steven E. Coutré, MD, Associate Professor Clinical evaluation of platelet antagonists, hematopoietic growth factors and novel antithrombotics Development of clinical protocols for the treatment of hematologic malignancies including acute and chronic leukemias and multiple myeloma



		Peter P. Lee, MD, Associate Professor Studying the T cell response to cancer (melanoma, leukemia, breast cancer, and others) using state-of-the-art tools such as peptide/MHC tetramers, 10-color FACS analysis, and DNA microarrays Design of novel strategies to modulate cancer-immune interactions Mathmatical/computer modeling of immune responses and cancer using non-linear dynamics and chaos theory



		Calvin Kuo, MD, PhD, Associate Professor Assessment of therapeutic efficacy of novel anti-angiogenic factors using adenoviral, knockout and corneal micropocket assays in mice Biology and signaling mechanisms of novel vascular G-protein coupled receptors in mice and zebrafish Roles of Wnt signaling in adult physiology using adenoviral and transgenic approaches


Assistant Professors

		Steven Artandi, MD, PhD, Assistant Professor Understanding how telomere shortening influences cell fates and how it leads to chromosomal instability and promotes initiation of tumoigenesis Characterizing how telomerase reactivation during tumor development facilitates cell survival and promotes tumor maturation Approaches to dissect oncogene and tumor suppressor function in the normal biology of the breast and in breast cancer formation using the mouse as a model system



		Jason R. Gotlib, MD, Assistant Professor Phase I/II trial evaluation of novel therapies for myelodysplastic syndromes, acute myelogenous leukemia, chronic myelogenous leukemia, and chronic myeloproliferative disorders (MPDs, eg. polycythemia vera, essential thrombocythemia, primary myelofibrosis, hypereosinophilic syndromes, and systemic mastocytosis) Translational research collaborations to interrogate the molecular basis of CML and chronic MPDs MPDs Associate Director, Stanford Myelodysplastic Syndromes Center Director, Hematology Division Tissue Bank Director, Med 8, Inpatient Hematology Service

Bruno Medeiros, MD, Assistant Professor

Development of novel therapeutic strategies for the treatment of myeloid, lympoid, acute and chronic leukemias as well as multiple myeloma

Michaela Liedtke, MD, Assistant Professor

Characterization of the molecular mechanism of MLL-induced acute leukemia and development of new therapeutic strategies for this disease
Design of phase I/II trials for the treatment of acute and chronic leukemia and multiple myeloma with novel experimental agents


Clinical Assistant Professors

		Caroline Bérubé, MD, Clinical Assistant Professor

Beth A. Martin, MD, Clinical Assistant Professor

Research interests include supportive care
Educational interests include malignancy: decision-making and communication skills; stress management; physical diagnosis
Clinical interests include multiple myeloma and general hematology-oncology

Instructors